• SimNIBS 2.0 is a free software package for the Simulation of Non-invasive Brain Stimulation. It allows for realistic calculations of the electric field induced by transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).

• SimNIBS 2.0 consists of two main parts:
  • A command line script is used for the automatic generation of tetrahedral volume meshes of the head from MR images.
  • These volume meshes are then used in the electric field calculations based on finite elements. A graphical user interface (GUI) is provided to set up the calculations.

• The Installation section describes how to download and set up SimNIBS under Ubuntu and Mac OS X.

• The Documentation section guides you through SimNIBS in a step-by-step fashion based on an example data set.

• Note: SimNIBS is a research tool. Clinical usage is not supported or advised. In particular, SimNIBS was not tested to give accurate results in the presence of pathological condition

SimNIBS was created at the Max-Planck Institute for Biological Cybernetics (Tübingen, Germany) and the Danish Research Center for Magnetic Resonance (Copenhagen, Denmark) (Contributors and Acknowledgements). SimNIBS is distributed under the GNU GPL v3. When you publish results based on SimNIBS 2.0 or parts of it, please cite:

• Thielscher, A., Antunes, A. and Saturnino, G.B. (2015), Field modeling for transcranial magnetic stimulation: a useful tool to understand the physiological effects of TMS? IEEE EMBS 2015, Milano, Italy

• 04/05/2016: Version 2.0.1 now available. The new version includes: anisotropic conductivity modeling from DTI data, advanced electrode modeling, coil distance setting, automated installation procedure for MacOSX, and bug fixes see the changelog for more details
• Version 2.0.0 is now available! We will continously improve it. So stay tuned and check out our web site from time to time!
• SimNIBS now has full support for tDCS. Our first paper making use of this is published in NeuroImage ("Determinants of the electric field during transcranial direct current stimulation")
• Our new paper "On the importance of electrode parameters for shaping electric field patterns generated by tDCS" was accepted for publication in NeuroImage. We're working on adding the advanced electrode models used in the paper to the SimNIBS package.
• Our new approach to derive the magnetic vector field for TMS coils from measurements was just accepted in BrainStimulation ("Transcranial magnetic stimulation: An automated procedure to obtain coil-specific models for field calculations"). We will add accurate coil models based on that approach for a range of coils to future SimNIBS releases.